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  简历:

  工作单位:中国科学院西北特色植物资源化学重点实验室,甘肃省天然药物重点实验室,中国科学院兰州化学物理研究所

  工作地址:中国甘肃省兰州市天水中路18号 邮编:730000

  电话: 0931-4968385

  E-mail: yjllzu@126.com; yangjl@licp.cas.cn

  教育经历:

  2007年9月-2012年6月:博士(有机化学),兰州大学功能有机分子化学国家重点实验室

  2003年9月-2007年6月:学士(化学),山东大学

  工作经历:

  2015年11月? : 研究员,中科院兰州化物所

  2014年12月-2015年9月:Postdoctoral Research Associate ,North Carolina A&T State University/North Carolina Research Campus,USA

  2013年3月-2014年11月:Postdoctoral Research Fellow,Seoul National University,Korea

  2012年9月-2013年2月:Postdoctoral Researcher,Chosun University,Korea

  研究方向:

  1.基于现代色谱技术的神经保护活性天然产物的快速发现新方法; 

    2.基于现代天然产物技术的神经保护活性天然产物的成药性研究与新药创制。

  代表论著:

  1.Jun Wang, Thi Kim Quy Ha, Yan-Ping Shi, Won Keun Oh*, Jun-Li Yang*, Hypoglycemic Triterpenes from Gynostemma pentaphyllum. Phytochemistry, 2018, 155(November), 171-181.

  2.Wei-Feng Wang, Jun-Li Yang*, Yan-Ping Shi. Quality Evaluation of Six Bioactive Constituents in Goji Berry based on Capillary Electrophoresis Field Amplified Sample Stacking. Electrophoresis, 2018, 39(16), 2117-2124.

  3.Wei-Feng Wang, Yin Qiang, Xian-Hua Meng, Jun-Li Yang*, Yan-Ping Shi. Ultrasensitive Colorimetric Assay Melamine based on in situ Reduction to Formation of CQDs-Silver Nanocomposite. Sensors and Actuators B: Chemical, 2018, 260, 808-815.

  4.Xian-Fei Zhang, Juan Chen, Jun-Li Yang*, Yan-Ping Shi*. UPLC-MS/MS Analysis for Antioxidant Components of Lycii Fructus based on Spectrum-effect Relationship. Talanta, 2018, 180, 389-395.

  5.Xuan Qi, Wei-Feng Wang, Jun Wang, Jun-Li Yang*, Yan-Ping Shi *. Highly Selective Colorimetric Detection of Putrescine in Fish Products Using O-Phthalaldehyde Derivatization Reaction. Food Chemistry, 2018, 259(-), 245-250.

  6.Jun Wang, Jun-Li Yang,* Pan-Pan Zhou, Xian-Hua Meng, Yan-Ping Shi. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). Journal of Agricultural and Food Chemistry, 2017, 65(29), 5926–5934.

  7.Yin Qiang, Wei-Feng Wang, Basanta Dhodary, Jun-Li Yang*. Zeolitic Imidazolate Framework 8 (Zif-8) Reinforced Macroporous Resin D101 for Selective Solid-Phase Extraction of 1-Naphthol and 2-Naphthol from Phenol Compounds. Electrophoresis, 2017, 38(13-14), 1685–1692.

  8.Lei-Lei Liu, Thi Kim Quy Ha, Wei Ha, Won Keun Oh, Jun-Li Yang*, Yan-Ping Shi*. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Journal of Natural Products, 2017, 80 (2), 298–307.

  9.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Ji Yeon Seo, Hyunju Kim, Junsoo Park, Won Keun Oh*. 3, 4-seco-28-Noroleanane Triterpenes from Camellia japonica Protect from Neurotoxicity in a Rotenone Model of Parkinson’s Disease. Tetrahedron, 2016, 72(23), 3240-3249.

  10.Jun-Li Yang, Basanta Dhodary, Thi Kim Quy Ha, Jinwoong Kim, Eunhee Kim, Won Keun Oh*. Three New Coumarins from Saposhnikovia divaricata and Their Porcine Epidemic Diarrhea Virus (PEDV) Inhibitory Activity. Tetrahedron, 2015, 71(28), 4651-4658.

  11.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Euisun Pyo, Ngoc Hieu Nguyen, Hyomoon Cho, Eunhee Kim, Won Keun Oh*. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. Journal of Medicinal Chemistry, 2015, 58(3), 1268-1280.

  12.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Kuk-Hwa Kim, Junsoo Park, Chul-Ho Lee, Young-Choong Kim, Won Keun Oh*. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax Ginseng. Journal of Natural Products, 2014, 77(7), 1615-1623.

  13.Jun Wang, Thi Kim Quy Ha, Yan-Ping Shi, Won Keun Oh*, Jun-Li Yang*, Hypoglycemic Triterpenes from Gynostemma pentaphyllum. Phytochemistry, 2018, 155(November), 171-181.

  14.Wei-Feng Wang, Jun-Li Yang*, Yan-Ping Shi. Quality Evaluation of Six Bioactive Constituents in Goji Berry based on Capillary Electrophoresis Field Amplified Sample Stacking. Electrophoresis, 2018, 39(16), 2117-2124.

  15.Wei-Feng Wang, Yin Qiang, Xian-Hua Meng, Jun-Li Yang*, Yan-Ping Shi. Ultrasensitive Colorimetric Assay Melamine based on in situ Reduction to Formation of CQDs-Silver Nanocomposite. Sensors and Actuators B: Chemical, 2018, 260, 808-815.

  16.Xian-Fei Zhang, Juan Chen, Jun-Li Yang*, Yan-Ping Shi*. UPLC-MS/MS Analysis for Antioxidant Components of Lycii Fructus based on Spectrum-effect Relationship. Talanta, 2018, 180, 389-395.

  17.Xuan Qi, Wei-Feng Wang, Jun Wang, Jun-Li Yang*, Yan-Ping Shi *. Highly Selective Colorimetric Detection of Putrescine in Fish Products Using O-Phthalaldehyde Derivatization Reaction. Food Chemistry, 2018, 259(-), 245-250.

  18.Jun Wang, Jun-Li Yang,* Pan-Pan Zhou, Xian-Hua Meng, Yan-Ping Shi. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). Journal of Agricultural and Food Chemistry, 2017, 65(29), 5926–5934.

  19.Yin Qiang, Wei-Feng Wang, Basanta Dhodary, Jun-Li Yang*. Zeolitic Imidazolate Framework 8 (Zif-8) Reinforced Macroporous Resin D101 for Selective Solid-Phase Extraction of 1-Naphthol and 2-Naphthol from Phenol Compounds. Electrophoresis, 2017, 38(13-14), 1685–1692.

  20.Lei-Lei Liu, Thi Kim Quy Ha, Wei Ha, Won Keun Oh, Jun-Li Yang*, Yan-Ping Shi*. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Journal of Natural Products, 2017, 80 (2), 298–307.

  21.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Ji Yeon Seo, Hyunju Kim, Junsoo Park, Won Keun Oh*. 3, 4-seco-28-Noroleanane Triterpenes from Camellia japonica Protect from Neurotoxicity in a Rotenone Model of Parkinson’s Disease. Tetrahedron, 2016, 72(23), 3240-3249.

  22.Jun-Li Yang, Basanta Dhodary, Thi Kim Quy Ha, Jinwoong Kim, Eunhee Kim, Won Keun Oh*. Three New Coumarins from Saposhnikovia divaricata and Their Porcine Epidemic Diarrhea Virus (PEDV) Inhibitory Activity. Tetrahedron, 2015, 71(28), 4651-4658.

  23.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Euisun Pyo, Ngoc Hieu Nguyen, Hyomoon Cho, Eunhee Kim, Won Keun Oh*. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. Journal of Medicinal Chemistry, 2015, 58(3), 1268-1280.

  24.Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Kuk-Hwa Kim, Junsoo Park, Chul-Ho Lee, Young-Choong Kim, Won Keun Oh*. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax Ginseng. Journal of Natural Products, 2014, 77(7), 1615-1623.

   专利:

  (1) 杨军丽,孟宪华,师彦平。一种枸杞中具有的抗阿尔茨海默病的酰胺类化合物及酰胺类化合物组分。发明专利,申请号201810340462.6,2018年04月16日。

  (2) 杨军丽,孟宪华,师彦平。一种枸杞中的酰胺类化合物及酰胺类化合物组分及其制备方法。发明专利,申请号201810340746.5,2018年04月16日。

  (3) 杨军丽,孟宪华,师彦平。具有SIRT1抑制活性的糖苷类化合物及其制备方法。发明专利,申请号201711215932.8,2017年11月28日。

  (4) 杨军丽,孟宪华,师彦平。一种利用花椒根枝提取物制备的足浴粉及其制备方法。发明专利,申请号201710526565.7,2017年6月30日。

  (5) 杨军丽,王伟峰,师彦平。一种检测鸟氨酸的比色分析方法,发明专利,申请号:201710078829.7,2017年2月14日。

  所获奖励:

  1. 2015年度甘肃省自然科学奖二等奖:重要中草药化学成分和生物活性研究(排名第二)

  团队承担科研项目:

  1.“植物源活性天然产物的快速发现与应用”(主持)

  2. 2016年度国家自然科学基金面上项目(81673325):“基于超滤质谱和超低温探头NMR技术的三种花椒属植物中SIRT1抑制剂的快速发现及其抗肿瘤活性研究”(2017-2020年,主持)

  3. 2017年度国家自然科学基金委员会与韩国国家研究基金会联合资助合作交流项目(81711540311):“中韩药用植物抗衰老活性分子研究”(2017-2019年,主持)

 

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