研究队伍/陈佳/全凯军/李辉/韩羊霞/王娟娟/强睿斌/关琪霞
科研与学术工作经历
2021/09-至今，中国科学院兰州化学物理研究所，中国科学院西北特色植物资源化学重点实验室，助理研究员
2019/01-2021/08，中国科学院兰州化学物理研究所，中国科学院西北特色植物资源化学重点实验室，研究实习员
研究方向
荧光纳米材料的设计合成及其生物分析应用研究
代表性研究成果
- Xingchen Liu#, Yangxia Han#, Guoxiu Wang, Yuting Wang, Jia Chen, Yang Shu*, Jian-Hua Wang, Hongdeng Qiu*, Facile Synthesis of Kadsura-shaped Covalent Organic Frameworks for Sensitive Detection and Effective Removal of 2,4,6-Trinitrophenol, ACS Applied Nano Materials, 2022, doi.org/10.1021/acsanm.2c00510.
- Yangxia Han, Yuxiang Wang, Xingchen Liu, Jia Chen, Hongdeng Qiu*, Green- and Red-Emitting Fluorescent Silicon Nanoparticles: Synthesis, Mechanism, and Acid Phosphatase Sensing, ACS Applied Bio Materials, 2022, 5, 295-304.
- Xingchen Liu#, Yangxia Han#, Yang Shu*, Jianhua Wang, Hongdeng Qiu*, Fabrication and application of 2,4,6-trinitrophenol sensors based on fluorescent functional materials, Journal of Hazardous Materials, 2022, 425, 127987.
- Haijuan Zhang#, Yangxia Han#, Yali Yang, Jia Chen, and Hongdeng Qiu*, Construction of a Carbon Dots/Cobalt Oxyhydroxide Nanoflakes Biosensing Platform for Detection of Acid Phosphatase, Langmuir, 2021, 37, 10529-10537.
- Min Na#, Yangxia Han#, Yonglei Chen*, Sudai Ma, Juanjuan Liu, Xingguo Chen*, Synthesis of Silicon Nanoparticles Emitting Yellow-Green Fluorescence for Visualization of pH Change and Determination of Intracellular pH of Living Cells, Analytical Chemistry, 2021, 93, 5185-5193.
- Yangxia Han, Kaijun Quan, Jia Chen, Hongdeng Qiu*, Advances and prospects on acid phosphatase biosensor, Biosensors and Bioelectronics, 2020, 170, 112671.
- Yangxia Han, Wenjuan Lv, Hongli Chen, Hui Li, Jia Chen, Zhan Li, Hongdeng Qiu*, Chiral fluorescent silicon nanoparticles for aminopropanol enantiomer: fluorescence discrimination and mechanism identification, Analytical Chemistry, 2020, 92, 5, 3949-3957.
- Yangxia Han, Jia Chen, Zhan Li, Hongli Chen, Hongdeng Qiu*, Recent progress and prospects of alkaline phosphatase biosensor based on fluorescence strategy, Biosensors and Bioelectronics, 2020, 148, 111811.
- Yangxia Han, Yonglei Chen, Jie Feng, Min Na, Juanjuan Liu, Yunxia Ma, Sudai Ma, Xingguo Chen*, Investigation of nitrogen content effect in reducing agent to prepare wavelength controllable fluorescent silicon nanoparticles and its application in detection of 2-nitrophenol, Talanta, 2019, 194: 822-829.
- Yangxia Han, Yonglei Chen, Juanjuan Liu, Xiaoying Niu, Yunxia Ma, Sudai Ma, Xingguo Chen*, Room-temperature synthesis of yellow-emitting fluorescent silicon nanoparticles for sensitive and selective determination of crystal violet in fish tissues, Sensors and Actuators B: Chemical, 2018, 263: 508-516.
- Yangxia Han, Yonglei Chen, Jie Feng, Juanjuan Liu, Sudai Ma, Xingguo Chen*, One-pot synthesis of fluorescent silicon nanoparticles for sensitive and selective determination of 2,4,6-trinitrophenol in aqueous solution, Analytical Chemistry, 2017, 89: 3001-3008.
- Jean Claude Munyemana, Jia Chen*, Xin Wei, Mohammad Chand Ali1, Yangxia Han, Hongdeng Qiu*. Deep eutectic solvent-assisted facile synthesis of copper hydroxide nitrate nanosheets as recyclable enzyme-mimicking colorimetric sensor of biothiols, Analytical and Bioanalytical Chemistry, 2020: 1-10.
- Min Na,& Siping Zhang,& Juanjuan Liu, Sudai Ma, Yangxia Han, Yong Wang, Yongxing He, Hongli Chen, and Xingguo Chen*, Environmental Samples by Ratiometric Fluorescence and Test Paper Based on Dual-emission Fluorescent Silicon Nanoparticles, Journal of Hazardous Materials, 2020, 386, 121956.
- Jia Chen, Xin Wei, Hao Tang, Yangxia Han, Mohammad Chand Ali,*, Zhan Li, Hongdeng Qiu*, Highly discriminative fluorometric sensor based on luminescent covalent organic nanospheres for tyrosinase activity monitoring and inhibitor screening, Sensors & Actuators: B. Chemical, 2020, 305, 127386.
- Yunxia Ma, Wenjuan Lv, Yonglei Chen, Min Na, Juanjuan Liu, Yangxia Han, Sudai Ma and Xingguo Chen, New Journal of Chemistry, 2019,43, 5070-5076.
- Min Na, Yonglei Chen*, Yangxia Han, Sudai Ma, Juanjuan Liu, Xingguo Chen*, Determination of potassium ferrocyanide in table salt and salted food using a water-soluble fluorescent silicon quantum dots, Food Chemistry, 2019, 288: 248-255.
- Stanislas Nsanzamahoro, Félicité Pacifique Mutuyimana, Yangxia Han, Sudai Ma, Min Na, Juanjuan Liu, Yunxia Ma, Cuiling Ren, Hongli Chen*, and Xingguo Chen, Highly selective and sensitive detection of catechol by one step synthesized highly fluorescent and water-soluble silicon nanoparticles, Sensors and Actuators B: Chemical, 2019, 281: 849-856.
- Juanjuan Liu, Yanyan Dong, Yunxia Ma, Yangxia Han, Sudai Ma, Hongli Chen, Xingguo Chen*, One-step synthesis of red/green dual-emissive carbon dots for ratiometric sensitive ONOO- probing and cell imaging, Nanoscale, 2018, 10: 13589.
- Yunxia Ma, Yonglei Chen*, Juanjuan Liu, Yangxia Han, Sudai Ma, and Xingguo Chen*，Ratiometric fluorescent detection of chromium(VI) in real samples based on dual emissive carbon dots, Talanta, 2018, 185: 249-257.
- Jie Feng, Yonglei Chen*, Yangxia Han, Juanjuan Liu, Sudai Ma, Huige Zhang, and Xingguo Chen*, pH-regulated synthesis of trypsin-templated copper nanoclusters with blue and yellow fluorescent emission, ACS Omega, 2017, 2: 9109-9117.
- Jie Feng, Yonglei Chen*, Yangxia Han, Juanjuan Liu, Cuiling Ren, and Xingguo Chen*, Fluorescent carbon nanoparticles: A low-temperature trypsin-assisted preparation and Fe3+ sensing, Analytica Chimica Acta, 2016, 926: 107-117.
- 马云霞，陈永雷*，纳敏，刘娟娟，韩羊霞，马素黛，陈兴国*.锌硼共掺杂碳点的制备及其在检测亚硫酸根中的应用［J］.武汉大学学报, 2020, 0258, 1-8.
- Jean Claude Munyemana, Jia Chen*, Yangxia Han, Shusheng Zhang, Hongdeng Qiu*, A review on optical sensors based on layered double hydroxides nanoplatforms, Microchimica Acta, 2021, 188: 80.
- Jean Claude Munyemana, Jia Chen*, Hao Tang, Yangxia Han, Juanjuan Wang, Hongdeng Qiu*, Discriminative Detection of Dopamine and Tyrosinase Based on Polydopamine Dots Triggered by Fenton-like Activity of Mn3O4 Nanoparticles, ACS Applied Nano Materials, 2021, doi.org/10.1021/acsanm.0c03448.
- 韩羊霞，陈佳，邱洪灯一种具有红色荧光的硅纳米颗粒的制备及在检测酸性磷酸酶中的应用，专利号：ZL 202111100683.4，申请日：2021-09-18。（已授权）
- 陈兴国，韩羊霞，陈永雷，高选择性测定痕量TNP的水溶性荧光硅纳米颗粒合成及应用，专利号：ZL 201610964476.6。（已授权）
主持和参与的基金：
1. 甘肃省青年科技基金计划，手性荧光硅纳米颗粒的合成及手性识别与机理研究，20JR10RA051,2021.02-2023.01,2万元，在研，主持
2.中科院CAS-JSPS合作交流项目，手性空间可控的荧光纳米材料的制备及对映选择性纳米生物成像和生物应用，2022.04-2025.03，45万元，在研，参与
3. 国家自然科学基金，面上项目，22074154，硅点修饰硅胶固定相的制备及其在核苷和核苷酸分离中的应用，2021.01-2024.12，63万元，在研，参加
4. 国家自然科学基金，面上项目，21675068，共价有机框架材料（COFs）涂层毛细管的制备及其在毛细管电泳分离和测定环境内分泌干扰物中的应用研究，2017.01-2020.12，96.848万，在研，参加
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