化学生物学领域

邵士俊  Shao Shijun

副主任,研究员

博士生导师

邵士俊,男,博士,研究员,博士生导师。19684月生。1990年毕业于浙江大学化学系,获理学学士学位;分别于1996年和2000年在中科院兰州化物所获理学硕士学位和博士学位。2001年入选中科院西部之光人才培养计划,2006年入选中科院西部之光联合学者。现任中科院兰州化物所甘肃省天然药物重点实验室副主任,《分析测试技术与仪器》杂志编委。主要研究领域为分子识别与分离分析新方法,中药和天然药物质控技术与质量标准研究。开展了合成受体分子设计及其分子识别与光化学传感;纳米材料修饰电极及其生物(药物)分子的电化学传感;道地中药材色谱指纹图谱质控技术与质量标准;组分中药新药和功能产品研发等研究工作。已在Biosens. Bioelectron.Electrochem. Commun.Electrochim. ActaOrg. Lett.Org. Biomol. Chem.Tetrahedron Lett.J. Chromatogr. ATalanta等刊物发表研究论文40多篇(SCI论文30多篇),申请发明专利8件(授权3件)。荣获2003年度第二届兰化所青年创新奖优秀奖。

主要研究方向:

分子识别与分离分析新方法;中药和天然药物质控技术与质量标准研究。

近期代表性论文

1.Guangzhi Hu, Yong Guo, Shijun Shao*, Ultrasensitive Electrochemical Sensing of the Anticancer Drug Tirapazamine Using an Ordered Mesoporous Carbon Modified Pyrolytic Graphite Electrode, Biosens. Bioelectron., 2009, 24, 3391-3394.

2.Long Chen, Guangzhi Hu, Guojun Zou, Shijun Shao*, Xiaolai Wang*, Efficient anchorage of Pd nanoparticles on carbon nanotubes as a catalyst for hydrazine oxidation, Electrochem. Commun., 2009, 11, 504-507.

3.Guangzhi Hu, Long Chen, Yong Guo, Shijun Shao*, Xiaolai Wang*, Selective electrochemical sensing of calcium dobesilate based on the nano-Pd/CNTs modified pyrolytic graphite electrode, Talanta, 2009, 78, 1211-1214.

4.Guangzhi Hu, Yong Guo, Shijun Shao*, Simultaneous Determination of Dopamine and Ascorbic Acid Using the Nano-Gold Self-Assembled Glassy Carbon Electrode, Electroanalysis, 2009, 21(10), 1200-1206.

5. Guangzhi Hu, Yonggen Ma, Yong Guo, Shijun Shao*, Selective electrochemical sensing of calcium dobesilate based on an ordered mesoporous carbon-modified pyrolytic graphite electrode, J. Electroanal. Chem., 2009, 633(1), 264-267.

6.Guangzhi Hu, Yonggen Ma, Yong Guo, Shijun Shao*, Electrocatalytic oxidation and simultaneous determination of uric acid and ascorbic acid on the gold nanoparticles modified glassy carbon electrode, Electrochim. Acta, 2008, 53, 6610-6615.

7.Shuzhen Hu,Yong Guo,Jian Xu and Shijun Shao*, A selective chromogenic molecular sensor for acetate anion in mixed acetonitrile/water medium, Org. Biomol. Chem., 2008, 6, 2071-2075.

8.Huaqiao Ma, Mina Luo, Shijun Shao, Xia Liu and Shengxiang Jiang*,Hydrogen-bond effect and ion-pair association in the separation of neutral calix[4]pyrroles by nonaqueous capillary electrophoresis, J. Chromatogr. A, 2008, 1188, 57-60.

9. Huaqiao Ma, Mina Luo,Shijun Shao, Xia Liu and Shengxiang Jiang*, Cation effects in the separation of calix[4]pyrroles by nonaqueous capillary electrophoresis with tetraalkyl- ammonium chloride salts as background electrolytes,J. Chromatogr. A, 2008, 1192, 180-186.

10.Kai Liu, Lijun He, Xiaoming He, Yong Guo, Shijun Shao*, Shengxiang Jiang, Calix[4]pyrrole-TCBQ Assembly: A Signal Magnifier of TCBQ for Colorimetric Determining Amino Acids and Amines, Tetrahedron Lett., 2007, 48, 4275-4279.

11.Shuai Wang, Hua-Qiao Ma, Ya-Jie Sun, Cheng-Dong Qiao, Shi-Jun Shao and Sheng-Xiang Jiang*,Fingerprint quality control of Angelica sinensis (Oliv.) Diels by high-performance liquid chromatography coupled with discriminant analysis, Talanta, 2007, 72, 434-436.

12.Xiaoming He, Shuzhen Hu, Kai Liu, Yong Guo, Jian Xu, Shijun Shao*, Oxidized Bis(indolyl)methane: A Simple and Efficient Chromogenic-Sensing MoleculeBased on theProton TransferSignaling Mode, Org. Lett., 2006, 8, 333-336.

联系方式:

中国科学院兰州化学物理研究所

甘肃省天然药物重点实验室

兰州市天水中路18号

邮编:730000

Email: sjshao@licp.cas.cn

电话:0931-4968209

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